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疼痛與炎癥研究

冷熱板儀

時間:2016-09-21來源:本站作者:玉研儀器

詳細介紹

冷熱板痛覺測痛儀(大小鼠冷熱板測試,冷熱板,Hot Cold Plate Analgesia Meter for Mice and Rats測量動物對鎮痛藥物的疼痛反應極限,同時進行冷熱痛覺測試,更多詳情敬請來電咨詢)


型號:39型(熱板儀)、PE34(冷熱板儀)

 

傳統的熱板測試只能測試動物疼痛反應時間,同時由于冷卻時間長不能用于溫度升高測試和重復測試。PE34采用微處理器控制溫度升高和降低,可以進行冷痛覺測試和熱痛覺測試,用于測量動物對鎮痛藥物的疼痛反應極限,擴大了鎮痛藥物研究的范圍。

 

冷熱板痛覺測試儀主要特點:

 

快速升溫和降溫,每分鐘可升降10℃,適合重復測試 溫度穩定性為0.1℃

溫度范圍從0到70℃

時間精度為0.01秒

冷熱板大?。?/span>4” x 8”

標準計算機打印口,輸出 RS-232輸出


Hot Cold Plate is used to measure the nociceptive threshold of analgesic compounds in mice and rats.

Conventional constant temperature hot plate tests only measure latencies of stronger narcotic agents.


Hot/Cold Plate Analgesia Meter widens the range of analgesia research to new levels. The unit is

microprocessor controlled and can be used for both incremental heating and cooling from any starting

temperature from 0 deg. c. to 70 deg. c in 0.1 degrees c. increments. The microprocessor monitors and

controls the rate of heating/cooling which can be set from 1 to 10 deg c. per minute. The front panel

display shows all test results including length of test in .01 sec. increments, starting temperature and

stopping temperature. The plate is uniformly heated/cooled at an adjustable rate and has automatic

upper/lower cut-off limits. All parameters are entered via front panel keypad. i.e. rate of temperature

increase/decrease, maximum/minimum temperature, date/time and animal number.



相關文獻:

[HTML] Cell cycle inhibition limits development and maintenance of neuropathic pain following spinal cord injury

J Wu, Z Zhao, X Zhu, CL Renn, SG Dorsey, AI Faden - Pain, 2016 - ncbi.nlm.nih.gov

… Hot and cold plate tests were used to assess the thermal hyperesthesia [8]. An incremental
hot/cold plate (PE34; IITC Life Sciences, Woodland Hills, CA) with a starting temperature of
30°C and the hot and cold ramps, set at the maximum rate of 10 °C/min, was used to induce …


Transient receptor potential vanilloid 1 mediates nerve growth factorinduced bladder hyperactivity and noxious input

B Frias, A Charrua, A Avelino, MC Michel… - BJU …, 2012 - Wiley Online Library

… for 5 min. Latencies were determined before and 4 h after each NGF injection. For
that, animals were placed on the hot-plate apparatus (Series 8, model PE34, IITC
Life Sciences, Woodland Hills, CA, USA). The platform was …


HTMLVoluntary exercise training: analysis of mice in uninjured, inflammatory, and nerve-injured pain states

TD SheahanBA Copits, JP Golden, RW Gereau IV - PloS one, 2015 - journals.plos.org

… Values from both paws were averaged to determine withdrawal latency. Hot plate.
Prior to testing day, animals were individually acclimated to the hot plate chamber
(Model PE34 Series 8, IITC Life Science Inc.) for 15 min. On …


[HTML] Evaluation of antinociceptive effect of methanolic leaf and root extracts of Clitoria ternatea Linn. in rats

L Kamilla, S Ramanathan, S Sasidharan… - Indian journal of …, 2014 - ncbi.nlm.nih.gov

… The hot plate test was used as previously described.[9] The heated surface of a hot plate analgesia
meter (model PE34, series 3, IITC Life Science Series, Woodland hills, USA) was maintained at
55 ± 1°C. Each animal was placed on the heated surface of the plate …


[PDF] Analgesic and antioxidant properties of ethanolic extract of Terminalia catappa L. leaves

HV AnnegowdaMN Mordi, S Ramanathan… - International journal of …, 2010 - academia.edu

… Rats were placed on the heated surface of a hot plate analgesia meter (IITC Life Science Series
8, Model PE34, Victory Blvd, Woodland Hills, CA 91367, USA) maintained at 55+0.2°C. The time
taken for licking, shaking of forepaws or jumping was recorded as the index of …


HV Annegowda, MN Mordi, S. Ramanathan and SM Mansor

ISI Thomson - International Journal of Pharmacology, 2010 - scialert.net

… Rats were placed on the heated surface of a hot plate analgesia meter (IITC Life Science Series
8, Model PE34, Victory Blvd, Woodland Hills, CA 91367, USA) maintained at 55±0.2°C. The time
taken for licking, shaking of forepaws or jumping was recorded as the index of …


[HTML] Modality-specific peripheral antinociceptive effects of μ-opioid agonists on heat and mechanical stimuli: Contribution of sigma-1 receptors

á Montilla-García, G Perazzoli, Má Tejada… - …, 2018 - Elsevier

… Then the plantar side of the stimulated hindpaw was placed on the surface of a thermal
analgesiometer (Model PE34, Series 8, IITC Life Science Inc., Los Angeles, USA) previously
set at 55 ± 1 °C until the animal showed a paw withdrawal response …

 



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