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熱板儀

時間:2016-09-21來源:本站作者:玉研儀器

詳細介紹

熱板痛覺測痛儀(大小鼠熱板儀,Hot Plate Analgesia Test Meter Mice and Rats)測試大鼠和小鼠的疼痛反應時間,進行快速精確地篩選麻醉型鎮痛藥物,更多詳情敬請來電咨詢)


型號:39型(熱板儀)、PE34(冷熱板儀)

 

熱板疼痛測試儀通過測試大鼠和小鼠的疼痛反應時間,進行快速精確地篩選麻醉型鎮痛藥物。如針對一組大鼠,在服用藥物前,測量該組大鼠在熱盤上舔爪的平均時間,該時間對應的是大鼠對熱刺激的反應時間,在服用鎮痛或麻醉藥物后,測量該組大鼠在熱盤上舔爪的平均時間,該時間對應的是大鼠服用藥物后對熱刺激的反應時間,對兩組時間值的比較,評估鎮痛或麻醉藥物對大鼠的效果。

 

Hot Plate Analgesia test is used for latency testing in rats and mice. The animals are placed on a black anodized, aluminum plate (11” X 10.5” X ?”, 275mm X 263mm X 15mm) which is heated uniformly.

 

熱板痛覺測試儀主要特點: 

 

可測量大鼠和小鼠 溫度步進量0.1攝氏度

控制保持精度+/- 0.1攝氏度

溫度范圍從0到75℃

時間精度為0.01秒

標準計算機打印口,輸出 RS-232輸出 

 

Dimensions:

Electronics - 18" X 18"

120/240V 

CE

Part #

Description

39

Hot Plate Analgesia Meter mice rats

39RE

Hot Plate Analgesia Meter Rat Enclosure (Square)

39ME

Hot Plate Analgesia Meter Mouse Enclosure (Round)

Series 8

Software





相關文獻:

Substitution of a mutant α2a-adrenergic receptor via “hit and run” gene targeting reveals the role of this subtype in sedative, analgesic, and anesthetic-sparing …

PP Lakhlani, LB MacMillan, TZ Guo… - Proceedings of the …, 1997 - National Acad Sciences

… B6,129 male mice, ≈3 months old, were placed on an enclosed hot-plate (IITC Inc.); the
temperature of the plate was ramped at 6°C/min from 43°C to 52°C. When a mouse licked a hind
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Hot plate versus tail flick: evaluation of acute tolerance to continuous morphine infusion in the rat model

L Langerman, MI Zakowski, B Piskoun… - … of pharmacological and …, 1995 - Elsevier

… The plate was adjusted to maintain a constant temperature of 52.5 + 0.2”C (Hot
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Neuroanatomical sites of action of neurotensin

PW Kalivas, CB Nemeroff… - Annals of the New York …, 1982 - Wiley Online Library

… Behavioral testing was begun one week after surgery. A hot plate (IITC, Inc., Model
35-D) was used to assess nociceptive threshold and was maintained at 55.0 -t 0.5"C.
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The behavioural effects of intrathecal galanin on tests of thermal and mechanical nociception in the rat

Z Wiesenfeld‐Hallin, XJ XU, JX HAO… - Acta physiologica …, 1993 - Wiley Online Library

… Only rats showing bilateral motor blockade were included in the study. The response of the rats
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Antinociceptive effects in mice after intrathecal injection of 5′-N-ethylcarboxamide adenosine

C Post - Neuroscience letters, 1984 - Elsevier

… The tail-flick test was performed with an IITC Model 33 Analgesiameter, and an IITC Model
35-D Analgesiameter for the hot-plate test. In the tail-flick test, the intensity of the light beam was
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Intra-paragigantocellularis lateralis injection of orexin-A has an antinociceptive effect on hot plate and formalin tests in rat

E Erami, H Azhdari-Zarmehri, E Ghasemi-Dashkhasan… - Brain research, 2012 - Elsevier

… minor modifications. In these experiments, the hot-plate (Analgesia meter IITC, Life
Science, USA) apparatus was maintained at 52±0.1 °C. The animals, presenting
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Antagonism of nitrous oxide antinociception in the rat hot plate test by site-specific mu and epsilon opioid receptor blockade.

BL Hodges, MJ Gagnon, TR Gillespie… - … of Pharmacology and …, 1994 - ASPET

… After a 5-mm exposure period, the animal was quickly removed from the box and dropped onto
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Hyperalgesia in mice lacking the Kv1. 1 potassium channel gene

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… hot plate assay was done as described by O'Callaghan and Holtzman [10]with equipment from
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Evaluation of the antinociceptive activity and acute oral toxicity of standardized ethanolic extract of the rhizome of Curcuma xanthorrhiza Roxb

S Devaraj, AS Esfahani, S Ismail, S Ramanathan… - Molecules, 2010 - mdpi.com

… [11] with slight modifications. The hot plate test was assessed by the Incremental Hot plate (IITC
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Intrathecal γ-aminobutyric acidB (GABAB) receptor antagonist CGP 35348 induces hypersensitivity to mechanical stimuli in the rat

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… and was averaged. The responses to noxious heat was tested by placing the rats
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